Find hotels near Mayo Clinic, Rochester from $79

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Compare 420 hotels close to Mayo Clinic with room rates, reviews, and availability. Most hotels are fully refundable.

Free daily buffet breakfast
TownePlace Suites by Marriott Rochester Mayo Clinic Area
3.0 star property
9.8 out of 10, Exceptional, (274)
"I appreciate the convenience of the location to Mayo Clinic. Staff were accommodating and friendly. Beds are very comfortable. "
The price is $118
$136 total
includes taxes & fees
Jun 1 - Jun 2
TownePlace Suites by Marriott Rochester Mayo Clinic Area
Courtyard
EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel
4.0 star property
9.6 out of 10, Exceptional, (581)
"Awesome"
The price is $106
$135 total
includes taxes & fees
May 23 - May 24
EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel
Terrace/patio
Home2 Suites by Hilton Rochester Mayo Clinic Area
3.0 star property
9.6 out of 10, Exceptional, (619)
"The service was great! The shuttle bus and driver were so helpful!"
The price is $127
$146 total
includes taxes & fees
May 26 - May 27
Home2 Suites by Hilton Rochester Mayo Clinic Area
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Lobby
Hilton Rochester Mayo Clinic Area
3.5 star property
9.6 out of 10, Exceptional, (333)
"All staff are nice and friendly "
The price is $169
$195 total
includes taxes & fees
May 31 - Jun 1
Hilton Rochester Mayo Clinic Area
Terrace/patio
The Berkman
3.0 star property
9.6 out of 10, Exceptional, (205)
"We needed a place for 7 people for a night. The ooo's and ahhh's as we explored our space said it all. There is no doubt that on our next visit we will try and stay at the Berkman again."
The price is $179
$208 total
includes taxes & fees
May 17 - May 18
The Berkman
Exterior
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
2.5 star property
9.6 out of 10, Exceptional, (504)
"Very close to Mayo"
The price is $89
$102 total
includes taxes & fees
May 31 - Jun 1
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
BBQ/picnic area
Residence Inn by Marriott Rochester Mayo Clinic Area South
3.0 star property
9.4 out of 10, Exceptional, (77)
"Great modern clean hotel in Rochester. The breakfast was great! Pool area was very clean. "
The price is $118
$136 total
includes taxes & fees
May 23 - May 24
Residence Inn by Marriott Rochester Mayo Clinic Area South
Terrace/patio
Hyatt House Rochester/Mayo Clinic Area
3.0 star property
9.0 out of 10, Wonderful, (536)
"I had an incredible time while staying there! The staff were great and went above and beyond to help me several times! Will definitely stay here again! "
The price is $111
$128 total
includes taxes & fees
May 31 - Jun 1
Hyatt House Rochester/Mayo Clinic Area
Terrace/patio
Hampton Inn Rochester-South
2.5 star property
9.0 out of 10, Wonderful, (1000)
"Great staff, clean room, friendly people. More parking or space for parking would have been more convenient for customers "
The price is $94
$109 total
includes taxes & fees
Jun 9 - Jun 10
Hampton Inn Rochester-South
Exterior
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
3.0 star property
9.0 out of 10, Wonderful, (615)
"A nice hotel at a reasonable rate. Our three night stay was very pleasant."
The price is $116
$134 total
includes taxes & fees
May 26 - May 27
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Exterior
Aspen Suites
3.0 star property
9.0 out of 10, Wonderful, (488)
"Neither of the bedside reading lights worked"
The price is $150
$181 total
includes taxes & fees
May 24 - May 25
Aspen Suites
Exterior
Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
3.5 star property
8.8 out of 10, Excellent, (532)
"Good location. I took an art workshop in town so this was a convenient location for my class. Room was small but well appointed. Some classmates also stayed at this hotel and they were on a noisy lower floor. Walls are thin so depending on the location of your room, it might be noisy. "
Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
Exterior
Holiday Inn Express & Suites Rochester – Mayo Clinic Area, an IHG Hotel
2.5 star property
8.8 out of 10, Excellent, (606)
"Courteous helpful staff. Only negative is syreet noise fron nearby highway "
The price is $112
$129 total
includes taxes & fees
May 17 - May 18
Holiday Inn Express & Suites Rochester – Mayo Clinic Area, an IHG Hotel
Exterior
Hilton Garden Inn Rochester Downtown, MN
3.0 star property
8.8 out of 10, Excellent, (665)
"Thank you"
The price is $118
$136 total
includes taxes & fees
May 25 - May 26
Hilton Garden Inn Rochester Downtown, MN
Indoor pool, sun loungers
AmericInn by Wyndham Rochester
2.0 star property
8.8 out of 10, Excellent, (893)
"Room was clean and quiet, nice pool and hot tub. Breakfast was good. Would definitely stay here againl."
The price is $79
$91 total
includes taxes & fees
May 31 - Jun 1
AmericInn by Wyndham Rochester
Exterior
Staybridge Suites Rochester - Commerce Dr NW, an IHG Hotel
3.0 star property
8.8 out of 10, Excellent, (387)
"this place was awesome. granted the hot tub and pool worked for 1 day we were there. we had to ask for towels once, and take out our own trash or ask for bags. but the staff was great food was perfect in thr morning. There was a light that was strobing but i just had my breakfast in the room. "
The price is $126
$145 total
includes taxes & fees
May 23 - May 24
Staybridge Suites Rochester - Commerce Dr NW, an IHG Hotel
Exterior
Holiday Inn Express Rochester South - Mayo Area, an IHG Hotel
2.5 star property
8.6 out of 10, Excellent, (1000)
"I really enjoyed this as a place to stay in Rochester! Easy parking, a delicious breakfast (pancakes, eggs, meat, oatmeal, fruit, cereal), and a workable gym (elliptical, bike, treadmill, dumbbells). Would stay again! "
The price is $91
$105 total
includes taxes & fees
Jun 2 - Jun 3
Holiday Inn Express Rochester South - Mayo Area, an IHG Hotel
Desk, iron/ironing board, free WiFi, bed sheets
Brentwood Inn & Suites
2.5 star property
8.6 out of 10, Excellent, (1000)
"Close to medical facilities, walkable"
The price is $109
$125 total
includes taxes & fees
May 17 - May 18
Brentwood Inn & Suites
Premium bedding, desk, iron/ironing board, free cribs/infant beds
Aspen Select
3.5 star property
8.6 out of 10, Excellent, (1000)
"Very close to Mayo Clinic. Across the street! Reasonable rate thru Expedia"
The price is $125
$159 total
includes taxes & fees
May 15 - May 16
Aspen Select
Exterior
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
3.0 star property
8.4 out of 10, Very Good, (624)
"Everything was good !"
The price is $109
$125 total
includes taxes & fees
May 24 - May 25
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What's the area like around Mayo Clinic?

Mayo Clinic is located in a welcoming area of Rochester known for its major shopping area. If you're looking for a convenient place to stay, check out the 164 hotels and other accommodations you'll find within a mile.

What's the best place to stay close to Mayo Clinic?

Adjacent to Mayo Clinic, Kahler Grand Hotel is one of the top choices for your stay based on our traveler data, and this hotel offers 3 restaurants and an indoor pool. Other good options close by include Kahler Inn and Suites - Mayo Clinic Area and EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel.

How many hotels will I be able to find near Mayo Clinic?

Expedia has 164 hotels and other accommodations within a mile from Mayo Clinic.

If I need to cancel the hotel reservation for my stay near Mayo Clinic, will I receive a refund?

Yes, you'll find most room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best deals near Mayo Clinic.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic?

For additional details about rescheduling or cancelling your stay near Mayo Clinic, head over to our customer service page.

What can I see and do near Mayo Clinic?

You'll want to browse the exhibits at Mayowood Mansion and History Center of Olmsted County. Learn about local history at Plummer House and Assisi Heights. You can enjoy live performances at Rochester Civic Theater and Marcus Rochester Cinema.