Find Resorts & Hotels with Spas in Mount Pleasant, SC

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Pick from 112 Mount Pleasant Resorts & Hotels with Spas and compare room rates, reviews, and availability. Most hotels are fully refundable.

Harborside at Charleston Harbor Resort and Marina
2 restaurants, lunch served
Harborside at Charleston Harbor Resort and Marina
4.0 star property
8.6 out of 10, Excellent, (1687)
"Love staying here"
The price is $153
includes taxes & fees
$135 per night
Nov 27 - Nov 28
Harborside at Charleston Harbor Resort and Marina
The Beach Club at Charleston Harbor Resort and Marina
Exterior
The Beach Club at Charleston Harbor Resort and Marina
4.5 star property
9.2 out of 10, Wonderful, (1005)
"Excellent"
The price is $250
includes taxes & fees
$221 per night
Nov 25 - Nov 26
The Beach Club at Charleston Harbor Resort and Marina
Best Western Patriots Point
Standard Room, 1 Queen Bed with Sofa bed, Non Smoking, Refrigerator & Microwave (with Sofabed) | Premium bedding, in-room safe, desk, laptop workspace
Best Western Patriots Point
2.5 star property
7.4 out of 10, Good, (1004)
"Check in was fast and efficient. Very friendly environment. Extremely clean room. Front desk person was very nice."
The price is $112
includes taxes & fees
$99 per night
Nov 3 - Nov 4
Best Western Patriots Point
Home2 Suites By Hilton Mt Pleasant Charleston
Exterior
Home2 Suites By Hilton Mt Pleasant Charleston
3.0 star property
8.8 out of 10, Excellent, (803)
"it was nice to have kitchen"
The price is $105
includes taxes & fees
$93 per night
Dec 1 - Dec 2
Home2 Suites By Hilton Mt Pleasant Charleston
Staybridge Suites Charleston - Mount Pleasant, an IHG Hotel
Exterior
Staybridge Suites Charleston - Mount Pleasant, an IHG Hotel
3.0 star property
9.4 out of 10, Exceptional, (874)
"Check-in was smooth and convenient, Staff was super-friendly and helpful. Amenities and dining were so much more than expected. A wonderful stay."
The price is $136
includes taxes & fees
$120 per night
Dec 1 - Dec 2
Staybridge Suites Charleston - Mount Pleasant, an IHG Hotel
Hotel Indigo Mount Pleasant, an IHG Hotel
Outdoor pool, free cabanas, sun loungers
Hotel Indigo Mount Pleasant, an IHG Hotel
3.5 star property
8.8 out of 10, Excellent, (1004)
"My wife and I always stay at the Indigo hotel when we visit Charleston.The front staff are always friendly and accommodating. The location of this hotel is convenient for us since we love to go to both historic downtown Charleston and also Isle of palms beach and also other places..so this hotel is centrally located in that you can easily jump on the highway and get to these places in less than 20 minutes (dependent on traffic/rush hour,etc.).Plus the pool is heated and designed nicely for...
The price is $140
includes taxes & fees
$126 per night
Nov 27 - Nov 28
Hotel Indigo Mount Pleasant, an IHG Hotel
Quality Inn Mt. Pleasant - Charleston
Seasonal outdoor pool, open 10:00 AM to 10:00 PM, sun loungers
Quality Inn Mt. Pleasant - Charleston
2.5 star property
8.4 out of 10, Very Good, (1056)
"The amenities weren’t top notch but registered this room five minutes out paid under $100 for the night and the bed was fantastic! Better bed than some luxury resort I stayed at in gatlinburg. Wish they’d run the ac in these rooms so they didn’t feel so damp and humid"
The price is $80
includes taxes & fees
$71 per night
Nov 25 - Nov 26
Quality Inn Mt. Pleasant - Charleston
Candlewood Suites Charleston Mt Pleasant, an IHG Hotel
Studio Suite, 1 King Bed | Private kitchen | Fridge, microwave, stovetop, dishwasher
Candlewood Suites Charleston Mt Pleasant, an IHG Hotel
2.5 star property
9.0 out of 10, Wonderful, (436)
"I don't normally leave reviews, but I had a great experience here! The staff were very warm and accommodating throughout my stay. The hotel was quiet and located near a variety of necessities/conveniences (i.e. Whole Foods), and the suite was big, clean, well-equipped, and comfortable. No complaints!"
The price is $99
includes taxes & fees
$88 per night
Dec 2 - Dec 3
Candlewood Suites Charleston Mt Pleasant, an IHG Hotel
Sleep Inn Mt. Pleasant - Charleston
Lobby
Sleep Inn Mt. Pleasant - Charleston
2.5 star property
7.6 out of 10, Good, (1004)
"Good place"
The price is $101
includes taxes & fees
$89 per night
Nov 28 - Nov 29
Sleep Inn Mt. Pleasant - Charleston
Tru by Hilton Mt Pleasant Charleston
Reception
Tru by Hilton Mt Pleasant Charleston
2.5 star property
9.4 out of 10, Exceptional, (1209)
"Liked my stay at Tru by Hilton. Only thing that could have improved my stay would be a better breakfast…especially larger selection of healthier foods."
The price is $103
includes taxes & fees
$91 per night
Dec 2 - Dec 3
Tru by Hilton Mt Pleasant Charleston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in Mount Pleasant?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travelers highly recommend the restaurants in Mount Pleasant. Enjoy the historical sites and riverfront during your vacation. Hotels with spas are the perfect way to break out of your daily routine and add a layer of luxury to your vacation.
What is the best spa hotel in Mount Pleasant?
The Beach Club at Charleston Harbor Resort and Marina is a highly recommended beach spa hotel featuring a 24-hour fitness center and an outdoor pool. Treat yourself to a body wrap, couples treatments, or massage at Estuary Spa.
How many spa hotels will I find in Mount Pleasant?
Among Expedia’s 346 accommodation options in Mount Pleasant, there is 1 spa hotel.
What's there to see and do in Mount Pleasant?
Experience Mount Pleasant with a stop at Mount Pleasant Towne Centre, Shem Creek Park, and Patriots Point. If you have a little extra time during your trip, you might want to check out USS Yorktown and Charleston Harbor Marina.
What is a Mount Pleasant spa hotel?
Spa hotels in Mount Pleasant provide lodging and have an on-site spa offering services including facials as well as beauty treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.